A multiple regression statistical model is applied to estimate the latitude and seasonal dependences of the solar cycle, quasi-biennial oscillation (QBO), and anthropogenic trend components of stratospheric total ozone change using 13.2 years of Nimbus 7 TOMS data. The characteristics of the linear trend component are in agreement with earlier studies. The QBO regression coefficient is significantly different from zero at high southern latitudes in the Austral spring supporting earlier evidence that the Antarctic ozone depletion is modulated by the QBO. The existence of a solar cycle component is indicated by empirical studies of model residuals and by the approximate agreement of the derived global mean solar coefficient amplitude with photochemical calculations. Initial estimates for the latitude dependence of the solar coefficient suggest higher amplitudes with increasing latitude, especially in the southern hemisphere in spring. The statistical model predicts a return to more rapid ozone depletions during the next 4 years as solar minimum is approached. ¿ American Geophysical Union 1992