Thermal infrared multispectral scanner (TIMS) images, acquired with side lapping flight lines, provide dual angle observations of the same area on the ground and can thus be used to estimate variations in the atmospheric transmission with scan angle. The method was tested using TIMS aircraft data for six flight lines with about 30% sidelap for an area within Joshua Tree National Park, California. Generally the results correspond to predictions for the transmission scan-angle coefficient based on a standard atmospheric model although some differences were observed at the longer wavelength channels. A change was detected for the last pair of lines that may indicate either spatial or temporal atmospheric variation. The results demonstrate that the method provides information for correcting regional survey data (requiring multiple adjacent flight lines) that can be important in detecting subtle changes in lithology.