Nighttime thermospheric winds have been measured from Ester Dome, near college, Alaska (64.8¿N, 147.8¿W), using the high-resolution Fabry-Perot interferometer of the University of Michigan Airglow Observatory. The winds are determined from the Doppler shifts of the (0 I) 15867 K (6300 ¿) line emission. Measurements obtained during geomagnetic quiet times in January and February 1972 are averaged to obtain the characteristic nighttime behavior of both the zonal and the meridional neutral wind components at F-region heights. Ion drifts during this period were measured by the Chatanika incoherent scatter radar facility. The measurements of the average nighttime zonal and meridional neutral wind components and of the average ion drift components are used with a three-dimensional dynamic model of the neutral thermosphere to determine the effectiveness of various forces in controlling the winds at F-region heights in the high-latitude thermosphere. A least squares fit of the measured and calculated nighttime variations of the zonal and meridional winds, using the ion drag determined from the radar measurements, gives the Fourier coefficients of latitudinal and longitudinal pressure gradients that are necessary to drive the observed wind pattern. The results show that the ion drag force is essentially balanced by the pressure force in the meridional direction. However, in the zonal direction the pressure force does not balance the ion drag force. The pressure gradients, derived in terms of exospheric temperature variations, show a differet nighttime variation from that predicted by the MSIS model for that latitude. The derived zonal winds are westward in the early evening hours, opposite of the winds calculated from a dynamic model that uses the pressure forces determined from the MSIS semiempirical model and ion drag.