Documented near-surface samples from oriented lunar rock 61016 have yielded the first measurements of depth profiles of 21Ne, 22Ne, and 38Ar isotopes produced in situ from nuclear interactions of energetic solar flare protons. Further, the cosmogenic 21Ne/22Ne ratios are distinct for different proton energy ranges and increase systematically with increasing shielding. This variation in cosmogenic 21Ne/22Ne represents a progression from a mixed component produced from solar flare protons (SCR) and galactic cosmic rays (GCR) to a pure GCR component. Using the 2 m.y. exposure age for 61016, the calculated production rates for SCR 21Ne and 38Ar from solar energetic protons in near-surface samples agree within 5% and 25%, respectively, with theoretical estimates. Calculated GCR production rates for 21Ne and 38Ar in the deepest (26 mm) samples agree within 25% and 10%, respectively, with theoretical estimates. Combined SCR and GCR concentration profiles for 21Ne, 22Ne, and 38Ar match theoretical calculations based on an omnidirectional flux above 10 MeV of 100 protons cm-2 s-1 with an exponential rigidity between 70 and 85 MV and a surface erosion rate of 1 mm m.y.-1. Selectively etched, near-surface samples suggest a long-term average 4He/3He ratio of ~770 for implanted solar flare nuclei with E>~4 MeV amu-1, and a 4He/3He ratio of ~3450 for solar flare nuclei with E>~1 MeV amu-1. Averaged over long term, the solar flare 4He/3He ratio appears energy dependent. ¿ American Geophysical Union 1993