The pattern of seismicity and fault plane solutions of earthquakes are used to outline the tectonic features of the southern boundary of Anatolia in the eastern Mediterranean and southeastern Turkey. The results of this study show that this boundary is composed of two distinct parts. One, in southeastern Turkey and Syria, is a wide and complex zone of continental collision. The other, in the Levantine basin of the eastern Mediterranean, is a zone of oceanic subduction. In the region of continental collision three zones of seismicity are observed. Most of the seismic activity in this region follows the Bitlis zone and is associated with a zone of thrusting and mountain building. This appears to be the zone of most active deformation and plate consumption in the plate boundary region between Arabia and Turkey. A less active zone of seismicity to the north of the Bitlis zone is interpreted to have been more active in the past whereas another active zone of seismicity to the south is interpreted to be a zone which may be more active in the future as the main zone of plate consumption jumps to the south. In the subduction zone of the eastern Mediterranean the depth of the subducted slab and the rate of seismicity generally increease from east to west. The zone of present-day convergence between Africa and Turkey in the Levantine basin can be best outlined by the northern edge of the Mediterranean ridge. The subduction zone in this area sequentially jumps to the south as small continental fragments collide with existing zones of subduction. Deep seismic activity near the Gulf of Antalya is associated with a detached subducted slab north of the Anaximander Mountains that is distinctly different from the seismic trend which is associated with present-day active subduction. The plate boundary between Africa and Turkey at the center of the Levantine basin appears to have shifted to the south of the Anaximander Mountains and Florence rise. Most of the focal mechanisms of the earthquakes along the entire southern boundary of Anatolia indicate that N to NNW thrusting is the dominant mode of seismic deformation. The present set of data is inconsistent with a major transform fault in the Cyprean arc east of Cyprus and in southeastern Turkey.