Andesite inclusions are found within the vent areas of two 600-year-old rhyolite domes in the Inyo craters volcanic chain, eastern California. Both domes lie within the present northwestern sector of 0.73 Ma Long Valley caldera. Inclusion morphology indicates that they were partially molten and ductile during incorporation within coarsely porphyritic rhyolite. The xenocryst assemblage within the inclusions (plagioclase+hornblende+biotite +quartz¿sanidine) is identical to the phenocryst assemblage within the host rhyolite. Microprobe analyses of xenocrysts within the andesite inclusions show that they have compositions similar to phenocrysts in host rhyolite. These data suggest that the andesite inclusions are the result of mixing of the coarsely porphyritic rhyolite with a more mafic end member. Whole rock geochemistry of the inclusions generally supports a simple mixing model between the coarsely porphyritic rhyolite of the Inyo domes and typical postcaldera mafic lavas found throughout the western caldera moat. The inclusions provide the first evidence for involvement of basaltic magma in the 600-year-old rhyolite eruptions of the Inyo Craters volcanic chain and suggest the possibility that the rhyolitic eruptions were initiated by injection of basalt into the lower part of the silicic magma system. Periodic thermal replenishment of the magmatic system through basaltic injection may explain the relatively high temperatures encountered in drill holes within the western caldera moat. The inclusions further suggest that although rhyolite eruptions are statistically more likely from the Inyo Craters volcanic chain, future basaltic eruptions cannot be ruled out. ¿ Amperican Geophysical Union 1990