Monoclines developed in the Colorado Plateau region during the Laramide orogeny are divided into western and eastern groups by a broad NNW trending antiform through the central part of the plateau. In the western group the major monoclines verge to the east, whereas in the eastern group the major monoclines verge to the west. Paleogeographic reconstruction based on paleocurrent indicators and sedimentary facies distribution suggests that the broad antiform was developed during the Laramide orogeny and was coeval with the formation of the monoclines in the plateau. This relationship implies that the monoclines were drag folds verging towards the center of the plateau as a response to the antiformal warping of the plateau. To simulate the warping of the plateau region and the stress distribution that produced the variable trends of the monoclines, an elastic thin plate model considering in-plane stress was developed. This model assumes that (1) sedimentation in the Laramide basins provided vertical loading along the edge of the plateau region, (2) frictional sliding was operating along the Laramide faults on the northern and eastern boundaries, and (3) the greatest regional compressive stress was oriented in the N60 ¿E direction and was applied uniformly along the western and southwestern sides of the plateau. Buoyancy due to instantaneous isostatic adjustment of crustal thickening or magmatic addition was also considered. The result of the model suggests that the frictional strength of the Uinta thrust system on the northern side of the plateau is at least 2 times greater than that along the Park Range and Sangre de Cristo thrust systems on the eastern side of the plateau in order to explain the observed monoclinal trends and the warping pattern within the plateau during the Laramide orogeny. ¿ American Geophysical Union 1994