During the last 10 m.y., the Nanga Parbat Haramosh Massif in the northwestern Himalaya has been intruded by granitic magmas, has undergone high-grade metamorphism and anatexis, and has been rapidly uplifted and denuded. As part of an ongoing project to understand the relationship between tectonism and petrologic processes, we have undertaken an isotopic study of the massif to determine the importance of hydrothermal activity during this recent metamorphism. Our studies show that both meteoric and magmatic hydrothermal systems have been active over the last 10 m.y. We suggest that the rapid uplift of the massif created a dual hydrothermal system, consisting of a near-surface flow system dominated by meteoric water and a flow regime at deeper levels dominated by magmatic/metamorphic volatiles. Meteoric fluids derived from glaciers near the summit of Nanga Parbat were driven deep into the massif along the transpressional faults causing Δ18O and ΔD depletions in the gneisses and marked oxygen isotopic disequilibrium between mineral pairs from the fault zones. The discharge of these meteoric fluids occurs in active hot springs that are found along the steep faults that border the massif. At deeper levels within the massif, infiltration of low Δ18O magmatic fluids caused Δ18O depletions in the gneisses within the migmatite zone. These low Δ18O fluids were derived from the young (<4 Ma), relatively low Δ18O granites (~8%0) that are found within the core of the massif. Geochronological evidence in the form of fission track and 40Ar/39Ar cooling ages and U/Pb ages on accessory minerals from the granites and gneisses provide a constraint on the timing of fluid flow in the surface outcrops we examined. Fluid infiltration in the migmatite zone rocks located along the Tato traverse was coeval with metamorphism, granite emplacement, and rapid denudation, in the interval 0.8--3.3 Ma. Finally, we infer from the presence of active hot springs that significant flow systems continue to be active at depth within the central portion of the Nanga Parbat-Haramosh Massif. ¿ American Geophysical Union 1995