Cl- depletion in sea-salt CCN was measured in chamber experiments after cloud formation in the presence of SO2 and O3. In each experiment, two successive clouds were formed on a sea-salt aerosol generated from the nebulization of filtered seawater, while chamber SO2 (g) and O3 (g) concentrations ranged from 4.8--8.3 ppb and 69--75 ppb. Particle growth from cloud processing reactions was measured with a differential mobility analyzer (DMA) immediately after cloud dissipation, and particles activated from dry radii of 0.02--0.03 μm showed growth to 0.08 and 0.12 μm, with total aerosol mass increases of 7.0 and 2.4 μg m-3 (assuming a particle density of 2.4 g cm-3). Particle growth was greater than that predicted by standard SO2-O3 oxidation kinetics and cannot be accounted for by the buffering capacity of the sea-salt CCN. Micro-orifice impactor (MOI) measurements of inorganic ions in the postcloud aerosol size distributions show, within analytical error, a 1:1 displacement of Cl- with nss-SO42-, until the SO42- is in excess and the Cl- is completely depleted at the smaller CCN sizes. Calculations of Cl- depletion, based upon the input size distribution and assuming particle growth via sulfate addition, show greater Cl- depletion on smaller size particles than the measured values. However, there is agreement within the uncertainty of the measured values. ¿ 2001 American Geophysical Union