Commercial mass flow controllers are widely used in atmospheric research where precise and constant gas flows are required. We have determined, however, that some commonly used controllers are far more sensitive to ambient pressure than is acknowledge in the literature of the manufacturers. Since a flow error can lead directly to a measurement error of the same magnitude, this is a matter of great concern. Indeed, in our particular application, were we not aware of this problem, our measurements would be subject to a systematic error that increased with altitude (i.e., a drift), up to a factor of 2 at the highest altitudes (~37 km). In this note we present laboratory measurements of the errors of two brands of flow controllers when operated at pressures down to a few millibars. The errors are as large as a factor of 2 to 3 and depend not simply on the ambient pressure at a given time, but also on the pressure history. In addition there is a large dependence on flow setting. In light of these flow errors, some past measurements of chemical species in the stratosphere will need to be revised. ¿ American Geophysical Union 1990