In the companion paper (part 1), theoretical studies on the dual frequency domain interferometry (FDI) technique have been presented. Two possible causes of biases in the layer thickness and position estimations by FDI have been considered: the limited extent of the scattering structure in the horizontal plane and the advection of this structure by the wind. In the present work, we study the effects of the tilts of the scattering layer from horizontal. It is shown that in case of large tilt angles, substantial biases on position and thickness can occur. The model, first developed by Liu and Pan <1993> but more extensively described in this paper, can also be used for a prediction of the variations of the FDI coherence with the zenith angle and their relation to the anisotropy of the scatterers. Some preliminary observations of the zenith angle dependence of the FDI coherence and echo power obtained with the middle and upper atmosphere (MU) radar from the vertical up to 28¿ off zenith with a step of 2¿ are shown and discussed. In principle, comparisons between the observed power and coherence variations with those given by the model could give more information on the structures that contribute around and far from the zenith. ¿ 2000 American Geophysical Union