Smog chamber/FTIR techniques were used to study the OH radical initiated oxidation of CF3CFHOCF3 in 700 torr of air diluent at 296 K. Relative rate techniques were used to measure k1(OH + CF3CFHOCF3) = (1.4 ¿ 0.3) ¿ 10-15 cm3 molecule-1 s-1. The atmospheric lifetime of CF3CFHOCF3 is estimated to be 40 years. The IR spectrum of CF3CFHOCF3 was measured and used to estimate a global warming potential (relative to CO2, 100 year time horizon) for CF3CFHOCF3 of 4500. Results are discussed with respect to the previous literature data.