Comparisons of remote sensing stratospheric mixing ratio profiles for O3, H2O, N2O, HNO3, and NO2 are shown between data (version 5.2) obtained by the Improved Limb Atmospheric Spectrometer (ILAS) on board the Japanese Advanced Earth Observing Satellite (ADEOS) and the Smithsonian Astrophysical Observatory far-infrared spectrometer (FIRS)-2 balloon-borne spectrometer from a flight on 30 April 1997 originating in Fairbanks, Alaska. Submillimeter wave remote sensing and UV in situ observations of mixing ratios of O3 from Jet Propulsion Laboratory (JPL) instruments obtained on board the same balloon gondola are also used for comparison with ILAS mixing ratios of O3. The remote sensing balloon observations occurred roughly 5¿ latitude, and the in situ 2¿ latitude, north of the nearest ILAS observations and were taken between 0700 and 1300 local solar time (LST), while the ILAS data were taken at the previous local sunset (near 2100 LST). Back trajectories from the locations and times of balloon data sets to the prior local sunset were within 2¿ latitude and 10¿ longitude of the nearest ILAS occultation; the validation therefore effectively occurred in very nearly the same air mass as was observed with ILAS, and well within a 1-day time interval. The mixing ratio profiles of all of the compared molecules (O3, HNO3, N2O, H2O, and NO2) agree to within the combined uncertainties with only minor systematic offsets.