A multiparameter investigation including organic carbon, carbonate, opal, and planktic foraminifera was carried out on five sediment cores from the coastal upwelling area between 24¿S and 33¿S along the Peru-Chile Current to reconstruct the history of the paleoproductivity and its driving mechanisms during the last 40,000 years. Inferred from our data, we conclude that the Antarctic Circumpolar Current as the main nutrient source in this region mainly drives the productivity by its latitudinal shifts associated with climate change. Simplified, its northerly position during the last glacial led to enhanced productivities, and its southerly position during the Holocene caused lower productivities. At 33¿S the paleoproductivity was additionally affected by the southern westerlies and records highest levels during the Last Glacial Maximum (LGM). North of 33¿S, several factors (e.g., position and strength of the South Pacific anticyclone, wind stress, continental runoff, and El Ni¿o Southern Oscillation events) supplementary influenced upwelling and paleoproductivity, where maximum values occurred prior to the LGM and during the deglaciation.