Accurate interpretation of SKS shear-wave splitting observations requires inherently indeterminate depth information. Magnetotelluric electrical anisotropies are depth-constrained, and thereby offer possible resolution of the SKS conundrum. MT and teleseismic instruments, deployed across the Great Slave Lake shear zone, northern Canada, investigated lithospheric anisotropy and tested a hypothesis that seismic and electrical anisotropy obliquity can infer mantle strain shear-sense. Lithospheric mantle MT strike (N60¿E) differs significantly from crustal MT strike (N30¿E). SKS splitting vectors outside the shear zone exhibit single-layer anisotropy with fast axis parallel to upper-mantle MT strike and oblique to present-day plate motion (N135¿W). Back-azimuth sensitivity at sites within the ~30 km wide shear-zone imply more complex layering, with two-layer inversion yielding an upper layer of ~N20¿E and a lower layer of ~N66¿E. The MT data help to constrain the depth location of SKS anisotropy and, taken together, support a model of fossil lithospheric anisotropy.