Estimates of ocean circulation constrained by in situ and remotely sensed observations have become routinely available during the past five years, and they are being applied to myriad scientific and operational problems <Stammer et al., 2002>. Under the Global Ocean Data Assimilation Experiment (GODAE), several regional and global estimates have evolved for applications in climate research, seasonal forecasting, naval operations, marine safety, fisheries, the offshore oil industry, coastal management, and other areas. This article reports on recent progress by one effort, the consortium for Estimating the Circulation and Climate of the Ocean (ECCO), toward a next-generation synthesis of ocean and sea-ice data that is global, that covers the full ocean depth, and that permits eddies.