We report on laboratory experiments designed to illuminate grain-scale deformation mechanisms within fault gouge. We vary particle size distribution, grain and surface roughness, and gouge layer thickness to better understand how grain sliding, rolling, dilation, and compaction affect the strength and stability of granular fault gouge. The experiments employed the double direct shear testing geometry and were run at room temperature, controlled humidity, and shearing rates from 0.1 to 3000 ¿m/s. Experiments were carried out under constant normal stress of 5 and 10 MPa and thus within a nonfracture loading regime where sliding friction for smooth, spherical particles is measurably lower than for rough, angular particles. We compare results from shear between smooth boundaries, where we hypothesize that grain boundary sliding is the dominant deformation mechanism, and roughened surfaces, where rolling and granular dilation contribute to shear deformation. We find that particle angularity and bounding surface roughness increase the frictional strength within sheared layers, indicating differences in particle reorganization due to these factors. In gouge material composed of <30% angular grains we observe repetitive stick-slip sliding where stress drop decreases while preinstability creep increases with increasing gouge layer thickness. Our data show significant differences in stick-slip characteristics as a function of gouge layer thickness and particle size, which we interpret in terms of the mechanics of grain bridges that support forces on the layers. We suggest that force chains exhibit qualitative differences as a function of grain angularity and bounding surface roughness.