To assess the status of global climate models (GCMs) in simulating upper-tropospheric ice water content (IWC), a new set of IWC measurements from the Earth Observing System's Microwave Limb Sounder (MLS) are used. Comparisons are made with ECMWF analyses and simulations from several GCMs, including two with multi-scale-modeling framework. For January 2005 monthly and daily mean values, the spatial agreement between MLS and ECMWF is quite good, although MLS estimates are higher by a factor of 2--3 over the Western Pacific, tropical Africa and South America. For the GCMs, the model-data agreement is within a factor of 2--4 with larger values of disagreement occurring over Eastern Pacific and Atlantic ITCZs, tropical Africa and South America. The implications arising from sampling and uncertainties in the observations, the modeled values and their comparison are discussed. These initial results demonstrate the potential usefulness of this data set for evaluating GCM performance and guiding development efforts.