We analyzed 2000--2004 growing-season SeaWinds Ku-band microwave backscatter and MODIS leaf area index (LAI) data over North America. Large anomalies in mid-growing-season mean backscatter and LAI, relative to 5-year mean values, occurred primarily in the western Great Plains; backscatter and LAI anomalies had similar spatial patterns across this region. Backscatter and LAI time series data for three ~103 km2 regions in the western Great Plains were strongly correlated (r2 ~ 0.6--0.8), and variability in mid-growing season values was well-correlated with annual precipitation (October through September). The results indicate that SeaWinds backscatter is sensitive to interannual variability in grassland biomass/productivity, and can provide an assessment that is completely independent of optical/near-infrared remote sensing instruments.