The 31 stations in the Global Positioning System (GPS) network of Switzerland span an altitude range of 330 to 3584 m. The highest station in the network, Jungfraujoch, suffers from a constant negative bias in the Integrated Water Vapor (IWV) due to a protective radome. We compared Jungfraujoch GPS IWV measurements with coincident Precision Filter Radiometer (PFR) observations and showed that the bias in the GPS is fairly constant with respect to the time of year and to the PFR IWV value. A correction was developed for the GPS data and validated by comparison with coincident Raman lidar observations. The IWV observations from nine GPS stations, including Jungfraujoch, were then compared with the IWV field of the ECMWF 40 year reanalysis (ERA40) data. Altitude differences between the ERA40 surface level and the GPS stations resulted, as expected, in a positive bias in the ERA40 IWV. A fairly linear relationship, with an intercept of -0.3 mm, was found between this bias and the difference between the ERA40 surface pressure and the surface pressure at the GPS station. The ERA40 reanalysis captured water vapor variations on timescales of several days very well, as evidenced by an r2 correlation greater than 0.9 where the altitude difference between ERA40 and the GPS station was less than 1000 m. A comparison between ERA40 and GPS at Davos showed that the reanalysis underestimates IWV during winter temperature inversions.