Spatial variations of gradients in landscapes may be used to identify and quantify recent deformation. The problem with doing this is to determine whether tectonic or climatic forcing is responsible for these variations, especially for low uplift rate environments ($ll$1 mm yr-1) where climate changes may have erased tectonic features. We evaluate the respective contribution of low uplift rate (~0.1 mm yr-1) and Pleistocene climate oscillations on gradient variations of two comparable river profiles crossing different uplift zones in the southern Upper Rhine Graben. We compare the observed points of discontinuity in river profile (knickpoints) and convex portions (knickzones) with those predicted by a detachment-limited model that includes stochastic short-term and cyclic long-term variations in climate, a bedrock detachment threshold and rock uplift. The detachment-limited model is chosen as it predicts the development of persistent knickpoints. Differing values of the shear stress exponent, erosion threshold, climate variability and uplift pattern have been checked. Our modeling suggests that climate changes had no significant effects on profiles and that anomalies are more likely due to anticline growth. This surprising result arises from the combination of a very low regional uplift rate and the detachment-limited assumption. The detachment-limited model implies an upstream propagation of knickpoints and knickzones generated by uplift at the outlet during dry climate periods of low erosion. The greater the uplift rate, the larger the variations in river bed elevation. Thus, for high uplift rate, knickpoints and knickzones generated by climate oscillations are more likely to hide tectonic features. This result seems counterintuitive because it suggests that tectonic knickzones will be better preserved in low uplift rate environments, provided that the lithology is homogeneous.