This paper presents the first measurements of the vertical distribution of CFC-22 in the stratosphere resulting from gas chromatography-mass spectrometry (GC-MS) of air samples collected cryogenically between 10 and 33 km altitude, at 44¿N. Results from 2 balloon flights carried out on September 10, 1983, are shown and compared with a theoretical profile computed by means of a 1-D model. Our results demonstrate that CFC-22 mixing ratios decrease more slowly with height than many other halocarbons indicating that this hydrohalcarbon may become an important source of ClOx radicals in the upper stratosphere.