This work presents a new implementation of the mixed potential integral equation (MPIE) for planar structures that can include ferrite layers arbitrarily magnetized. The implementation of the MPIE here reported is carried out in the space domain. Thus it will combine the well-known numerical advantages of working with potentials as well as the flexibility for analyzing nonrectangular shape conductors with the additional ability of including anisotropic layers of arbitrarily magnetized ferrites. In this way, our approach widens the scope of the space domain MPIE and sets this method as a very efficient and versatile numerical tool to deal with a wide class of planar microwave circuits and antennas.