Ionospheric plasma density depletions or 'holes' are observed by the Pioneer Venus orbiter in associaiton with radial magnetic fields in the near wake of Venus. This report presents examples of the collected observations of these unexpected features of the Venus nightside ionosphere obtained by the Langmuir probe, magnetometer, ion mass spectrometer, retarding potential analyzer, plasma analyzer, and electric field experiments. The connection between plasma density depletions and temperature changes, changes in ion composition, plasma wave emissions, and magnetic fields with a substantial radial component is illustrated. Mechanisms that may be reponsible for the formation and maintenance of holes are suggested.