Voyager radio occultation and infrared spectrometer measurements are used to obtain an estimate of the helium abundance in the atmosphere of Neptune. It is found that the shape of the measured spectrum cannot be well matched by spectra calculated from atmospheric models that include only gaseous opacity. The most plausible explanation of the observed spectral shape appears to require the existence of an additional opacity source associated with clouds or hazes. The data can be fit with either a tropospheric or a stratospheric cloud model. If a tropospheric cloud is invoked, an optical thickness at 200 cm-1 between 1 and 8 is required, depending on the particle size assumed. For a stratospheric cloud an optical thickness between 0.2 and 0.8 is required. Optical constants for methane ice are used, but ethane has similar optical properties in this spectral region. Assuming no modification to the temperature profile is required other than a molecular weight adjustment, a combination of gas and cloud opacities produces a good fit to the spectrum for a helium mole fraction qHe=0.190¿0.032, corresponding to a mass fraction Y=0.32¿0.05. Within the measurement uncertainties the Neptune helium abundance may be compatible with that of Uranus and, marginally, with the protosolar value. However, models in which the outer part of the primitive solar nebular was enriched in CO and N2, leading to an enhanced atmospheric He/H2 ratio, cannot be ruled out at this time. ¿ American Geophysical Union 1991