Laboratory measurements of rock strength provide limiting values of lithospheric stress, provided that one effective principal stress is known. Fracture strengths are too variable to be useful; however, rocks at shallow depth are probably fractured so that frictional strength may apply. A single linear friction law, termed Byerlee's law, holds for all materials except clays, to pressures of more than 1 GPa, to temperatures of 500 ¿C, and over a wide range of strain rates. Byerlee's law, converted to maximum or minimum stress, is a good upper or lower bound to observed in situ stresses to 5 km, for pore pressure hydrostatic or subhydrostatic. Byerlee's law combined with the quartz or olivine flow law provides a maximum stress profile to about 25 or 50 km, respectively. For temperature gradient of 15 ¿K/km, stress will be close to zero at the surface and at 25 km (quartz) or 50 km (olivine) and reach a maximum of 600 MPa (quartz) or 1100 MPa (olivine) for hydrostatic pore pressure. Some new permeabiltiy studies of crystalline rocks suggest that pore pressure will be low in the absence of a thick argillaceous cover.