The magnetization of 22 granitic and gneissic southern Appalachian rock units, with estimated cooling ages of 415--250 m.y., has been determined. Included are 842 samples from 114 sites within 19 granites (100 sites) and 3 gneisses (14 sites) located in North Carolina, South Carolina, and Georgia. Samples from 57 of these sites in 14 granites and 3 gneissic bodies yield a remanent magnetism after af demagnetization which exhibits good within-site and/or between-site directional consistency. Data for units which cooled to temperatures 20,000 km2 in size. The southeastern extent of this block is unknown due to Costal Plain onlap. A mean paleopole for this group, with corrections for maximum tilt estimates, exhibits good precision but has a paleosite latitude of ~10¿N. Without tilt correction the paleopole for group B still exhibits an anomalous paleosite latitude of ~4¿N. These data indicate that the group B block (Elberton-Sparta Crustal Block) lying to the SE has an apparent paleosite latitude corresponding to magnetization at a location to the north of the zone containing group A units. The preferred explanations for these data are (1) a northwest postemplacement tilting of the Elberton-Sparta Crustal Block during the Alleghenian orogenic event in the southeastern Appalachians, or (2) emplacement as a microplate caught between North America and Africa during the collision of these continental masses. Both interpretations appear to be consistent with the available geological, geochemical, and geophysical data for the area. Of those granites which comprise a ~400-m.y.-old group, only one granite. Lowrys, in South Carolina, exhibits good within-site and between-site precision. A paleopole calculated for the sites sampled in this unit exhibits fair precision and is consistent with magnetization acquisition as part of North America in Middle Paleozoic time.