Basement rocks of the Transantarctic Mountains are believed to record a change in the paleo-Pacific margin of Gondwana from a passive to a tectonically active margin. Widespread emplacement of calc-alkaline batholiths (Granite Harbor intrusives) occurred during the active margin phase. We present new concordant zircon and titanite U-Pb ages for these magmatic rocks in southern Victoria Land and the Scott Glacier area. Most magmatic rocks previously associated with a pre-late Early Cambrian (>530 Ma) deformational event(s) (Beardmore orogeny) have yielded younger crystallization ages. The lack of definite arc magmatism prior to ~530 Ma suggests that deformation may have been associated with a strike or oblique-slip regime, although shallow subduction without significant arc magmatism cannot be ruled out. Local transpressional and transtensional domains may account for compressional deformation and rare alkaline and carbonatite magmatism during this early period. The oldest and most voluminous magmatic rocks were emplaced after ~530 Ma. This magmatism has been associated with active subduction, and suggests a fundamental change in the plate boundary at ~530 Ma. Ductile shearing of plutons and contractional deformation of supracrustal rocks after ~530 Ma (Ross orogeny) may have been due to transpressional tectonics in an oblique subduction setting and/or a collision. Compressional deformation associated with the Ross orogeny may have ceased by ~500 Ma along the southern Victoria Land-Scott Glacier segment of the Antarctic margin, as indicated by undeformed magmatic rocks of this age, although magmatic activity continued to at least ~485 Ma. ¿ American Geophysical Union 1996